Atopic dermatitis (eczema)
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YouTubeMedLecturesMadeEasy
Atopic dermatitis (eczema)
Path: Mutation in epidermal barrier proteins (eg, filaggrin) leads to ↓ water content, ↑ permeability, ↑ inflammation; Immune dysfunction (ie, Th2-skewed response) Symptoms: Acute: pruritic, erythematous patches & papules Infants: red extensor surfaces, trunk & face Children & adults: flexor surfaces Chronic: lichenified plaques ...
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