Four pillars of heart failure: contemporary ... - Open Heart
Mar 2, 2021 · The past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF). 1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a background of an ageing and increasingly ...
Myo-inositol for insulin resistance, metabolic syndrome, polycystic ...
Mar 1, 2022 · Myo-inositol, also known as inositol (cyclohexanehexol), is a cyclic carbohydrate with six hydroxyl groups.1 For a long time, it was considered a B vitamin (vitamin B8). However, it is not considered an essential nutrient because it is formed from glucose. Each kidney makes around 2 g of myo-inositol per day, and the average dietary intake is 0.5–1.0 g/day.2 3 The liver and brain also ...
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Open Heart. is an open access journal by BMJ and BCS, publishing original research in cardiovascular medicine. Impact Factor: 2.8 Citescore: 4.6 All metrics >>
Amlodipine in hypertension: a first-line agent with efficacy for ...
Sep 27, 2016 · Objectives Hypertension is well established as a major risk factor for cardiovascular disease. Although there is undeniable evidence to support the beneficial effects of antihypertensive therapy on morbidity and mortality, adequate blood pressure management still remains suboptimal. Research into the treatment of hypertension has produced a multitude of drug classes with different efficacy ...
Magnesium for the prevention and treatment of cardiovascular …
Jun 30, 2018 · Magnesium is an essential mineral found in the body. It is naturally present in many foods and is also available as a dietary supplement. 1 It serves as a cofactor in more than 300 enzymatic reactions, such as those responsible for regulating blood pressure, glycaemic control and lipid peroxidation. It is therefore also critical to the cardiovascular system.1 The adult body contains ...
Transcatheter mitral valve repair: an overview of current and future ...
Apr 27, 2021 · The field of transcatheter mitral valve repair (TMVr) for mitral regurgitation (MR) is rapidly evolving. Besides the well-established transcatheter mitral edge-to-edge repair approach, there is also growing evidence for therapeutic strategies targeting the mitral annulus and mitral valve chordae. A patient-tailored approach, careful patient selection and an experienced interventional team is ...
Vitamin K2—a neglected player in cardiovascular health: a …
Nov 16, 2021 · Vitamin K2 serves an important role in cardiovascular health through regulation of calcium homeostasis. Its effects on the cardiovascular system are mediated through activation of the anti-calcific protein known as matrix Gla protein. In its inactive form, this protein is associated with various markers of cardiovascular disease including increased arterial …
Pentoxifylline for vascular health: a brief review of the literature ...
Pentoxifylline improves the rheological properties of blood in multiple ways. Pentoxifylline is a methylxanthine derivative used for the past three decades to treat intermittent claudication.1–3 In clinical doses—typically 400 mg three times daily—it improves the rheological properties of blood in numerous ways: decreasing plasma and whole blood viscosity, in large measure owing to a ...
Harnessing the power of clinical decision support systems: …
Nov 28, 2023 · Clinical decision support systems (CDSSs) are increasingly integrated into healthcare settings to improve patient outcomes, reduce medical errors and enhance clinical efficiency by providing clinicians with evidence-based recommendations at the point of care. However, the adoption and optimisation of these systems remain a challenge. This review aims to provide an overview of the current state ...
Echocardiographic diagnosis of right-to-left shunt using ...
Aug 5, 2020 · Introduction. Patent foramen ovale (PFO) is a common finding with a prevalence of about 25% in the general population.1 A strong association between PFO and ischaemic stroke has been reported.2 Pulmonary arteriovenous malformation (PAVM) is a rare disease in the general population and causes a permanent right-to-left shunt (RLS).3 The association of pulmonary RLS grade on contrast ...