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  1. Metastatic HER2-Positive Breast Cancer - WebMD

    Mar 16, 2023 · Here's everything you need to know if you or someone you love has just gotten a diagnosis of metastatic HER2-positive breast cancer.

  2. HER2-Positive Breast Cancer: Symptoms & Treatment

    HER2-Positive Breast Cancer HER2-positive (HER2+) breast cancer affects some people who have invasive breast cancer. This is a fast-growing cancer that can quickly spread from your …

  3. How we treat patients with metastatic HER2-positive breast cancer

    HER2-positive breast cancer represents 15%-20% of breast malignancies and is characterized by an aggressive behavior and high recurrence rates. Anti-HER2-directed agents represent the …

  4. Current Treatment Approaches in HER2+ Metastatic Breast Cancer

    Jun 17, 2025 · Panelists discussed how evolving strategies in HER2-positive metastatic breast cancer are shifting toward more personalized maintenance approaches, including the …

  5. HER2-Targeted Therapies for Metastatic Breast Cancer

    Mar 3, 2025 · HER2-Targeted Therapies for Metastatic Breast Cancer Watch our June 2024 MBC Impact Series, Metastatic HER2-Positive Breast Cancer. HER2 and metastatic breast cancer …

  6. DESTINY-Breast09: Trastuzumab Deruxtecan Plus Pertuzumab Sets …

    Jun 2, 2025 · Dr. Sara M. Tolaney Key Points: DESTINY-Breast09 is the first trial in more than a decade to demonstrate a clinically meaningful improvement in outcomes for a broad group of …

  7. FDA Approves Novel Interchangeable Biosimilar for Pertuzumab in HER2

    Nov 13, 2025 · Key Takeaways Pertuzumab-dpzb is the first interchangeable biosimilar to pertuzumab, enhancing treatment accessibility for HER2-positive breast cancer. The biosimilar …

  8. Expert consensus on treating HR+/HER2- metastatic breast cancer

    Dec 18, 2024 · Hormone receptor-positive, HER2-negative metastatic breast cancer (HR+/HER2-mBC) is incurable, but recent progress has been made in developing new treatment options …

  9. The evolving HER2+ metastatic breast cancer landscape: Novel …

    Dec 16, 2022 · Recent therapeutic advances in HER2-positive metastatic breast cancer (MBC) have begun to reshape the treatment landscape for patients. Since late 2019, the U.S. Food …

  10. Treatment of Stage IV (Metastatic) Breast Cancer

    Systemic (drug) treatments for stage IV breast cancer Treatment often continues until the cancer starts growing again or until side effects become unacceptable. If this happens, other drugs …