Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 ...

The offense looked like it misses Christian McCaffrey but the defense was surprisingly exposed. Now that Deebo Samuel is hurt ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

When Christian McCaffrey went down, the 49ers could take solace in the fact that they had another versatile and dynamic ...

Former 49ers players Richard Sherman and Donte Whitner ripped San Francisco's defense for allowing Justin Jefferson's 97-yard ...

This is the live blog for the San Francisco 49ers' Week 2 road game against the Minnesota Vikings. This will be updated ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

Sam Darnold passed for 268 yards and two touchdowns against his former team, including a 97-yard strike in the second quarter ...

The 49ers and Vikings had two of the Top 5 most impressive wins during Week 1 of the NFL season, but only one can come away 2 ...