Tuberous sclerosis complex and von Hippel–Lindau disease are distinct autosomal dominant tumor suppressor syndromes that can exhibit similar renal phenotypes and seem to share some signaling ...

Thiele, MD, PhD, Director, Tuberous ... sclerosis complex. One thing that stood out is the idea that this old notion that if your initial sonogram of the kidney doesn't show a tumor, then you ...

A garden that was designed to raise awareness for the Tuberous Sclerosis Association has won a gold medal at the RHS Chelsea Flower Show. Jen Donnelly and Catherine Gibbon volunteer at Amersham ...

aQueen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK bMedical Research ...

Objective This study was aimed to explore parents’ experience of assisting children affected by tuberous sclerosis complex (TSC) with subependymal giant-cell astrocytoma (SEGA) manifestation, in order ...

Moreover, PTGS2 was associated with tumor growth. Then, MALAT1 ... PTGS2 Expression Level and Immune Cell Infiltration as Well as Immunomodulators in Systemic Sclerosis-Interstitial Lung Disease ...

aNeurology Epilepsy and Movement Disorders Unit, Bambino Gesu’ Children’s Hospital, IRCCS, Full Member of European Reference Network on Rare and Complex Epilepsies, EpicARE, Rome, Italy ...

Introduction: Tuberous sclerosis complex (TSC) is a multisystem neurocutaneous disorder. Angiofibromas (AF), fibrous plaques, and hypopigmented macules are the major skin findings in TSC. Topical ...

Tuberous sclerosis complex (TSC) is an autosomal dominant disease ... the hyperactivation of the mTOR pathway leads to abnormal tissue proliferation and the development of solid tumors. Kidney ...

pointed to the diagnosis of tuberous sclerosis complex (TSC). TSC is a genetic disorder characterized by the presence of cerebral tumors, periungal and gingival fibromas, retinal phakomas ...