Europe PMC1mon
The zinc finger protein ZFP36L2 inhibits flavivirus infection via the 5'-3' XRN1-mediated RNA decay pathway in the replication complexes.
ZFP36L1 combats flavivirus infections through the 5'-3' XRN1 and 3'-5' RNA exosome decay pathways. The present study clarified the role of human ZFP36L2 in the defense response of the host against ...
eLife7mon
Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection
This study presents a valuable finding on the viroporin activity of the ZIKV M protein. The evidence supporting the claims of the authors is solid. The work will be of interest since M protein could ...
Frontiers2y
Molecular survey of Zika virus in the animal-human interface in traditional farming
Prior to the molecular detection of ZIKV, a preliminary screening was carried out to determine the presence of flavivirus in the collected samples. Reverse transcription (RT) was performed with 9.5 μl ...
Frontiers3y
Inhibition of Tryptophan Catabolism Is Associated With Neuroprotection During Zika Virus Infection
ZIKV is an arbovirus belonging to the family Flaviviridae, genus Flavivirus, composed of positive sense, single-stranded RNA. ZIKV was first isolated from a rhesus monkey in 1947 in the Zika forest ...
The Scientist8y
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Mount Sinai’s Jean Lim, Florian Krammer, Adolfo Garcia-Sastre, and their colleagues collected plasma samples from more than 200 people who were previously infected with dengue or West Nile virus, a ...
Medscape13y
Molecular Diagnosis of Flaviviruses
The genus Flavivirus includes major pathogens such as dengue, yellow fever, Japanese encephalitis, West Nile and tick-borne encephalitis viruses. Molecular amplification assays for the diagnosis ...