ABSTRACT: In this paper, we study a three-dimensional target-mediated drug disposition model consisted of the drugs (ligands), targets (receptors) and drug-target (ligand-receptor) complexes. In this ...

Discover how to build a homemade rubber band-powered paper airplane in this easy and engaging tutorial. We’ll guide you step-by-step as you craft the frame with skewers, add aerodynamic paper wings, ...

Study in a Sentence: The U.S. Food and Drug Administration approved an Investigational New Drug (IND) application using efficacy data solely from Qureator’s human vascularized organoid model, moving ...

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in ...

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure. Another example, ...

The Centers for Medicare & Medicaid Services (CMS) late last week announced the creation of the GENErating cost Reductions for US (GENEROUS) Medicaid Model, which will utilize most-favored nation ...

The GENEROUS Model aims to reduce Medicaid drug costs by aligning prices with international standards, launching in 2026. It builds on existing programs like the Medicaid Drug Rebate Program and the ...

Carrum Health launched a substance use disorder treatment program for employers a year ago and has now expanded it to include cannabis, cocaine and methamphetamine as employer demand surges. This ...

Cigna Group is launching a new rebate-free pharmacy benefit model which aims to bring down drug costs and simplify the payment process. Through its subsidiary Evernorth Health Services, a health ...

Substance use and substance use disorder differ by the frequency of use and the effect on a person’s life. Substance use disorder is a mental health condition. Substance use refers to using both legal ...