Among participants with no history of major psychopathology, there is no association between semaglutide and depression and suicidality.

Researchers examined data from the Semaglutide Treatment Effect in People with obesity (STEP) trials – STEP 1, 2, 3, and 5.

Taking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders, ...

Fink-Jensen, A. (2024). Psychiatric Safety of Semaglutide for Weight Management in People Without Known Major Psychopathology: Post Hoc Analysis of the STEP 1, 2, 3, and 5 Trials. JAMA Internal ...

Researchers examined data from the Semaglutide Treatment Effect in People with obesity (STEP) trials—STEP 1, 2, 3, and 5. These studies were crucial in gaining approval from the FDA to use ...

Taking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or ...

Treatment with semaglutide does not increase the risk for developing symptoms of depression or suicidal ideation/behavior ...

Researchers examined data from the Semaglutide Treatment Effect in People with Obesity (STEP) trials – STEP 1, 2, 3, and 5. These studies were crucial in gaining approval from the FDA to use ...

Severe obesity is already a significant problem for many children, especially since obese children often become obese adults. Could the now popular weight-loss injection drugs be a solution for those ...

The researchers found that in the STEP 1, 2, and 3 trials, the mean baseline Patient Health Questionnaire (PHQ-9) scores were 2.0 and 1.8 for semaglutide and placebo, respectively, and the mean ...