And then there’s the paucity of known RNA structures. The Protein Data Bank, a repository of 3D macromolecular structures, contains nearly 200,000 protein structures and fewer than 2,000 RNAs.

performing RNA sequencing (gene expression analysis) on each section, and superimposing the expression data to reconstruct a 3D gene expression map. However, processing this data requires advanced ...

SINGAPORE – A new programme has been launched in Singapore to formally study the applications of ribonucleic acid (RNA) in vaccine development, as well as in disease therapy and prevention ...

Researchers say they have mapped more than 200,000 cells in a cubic millimeter of brain tissue and have traced how they're ...

From a tiny sample of tissue no larger than a grain of sand, scientists have come within reach of a goal once thought unattainable: building a complete functional wiring diagram of a portion of the ...

Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

In 1979, famed molecular biologist Francis Crick stated that it would be “impossible to create an exact wiring diagram for a ...

Schematic diagram of the working principle of the tetrahedra DNA nanomachine ... The system also showed high specificity, responding to microRNA-7 but not to unrelated RNA sequences. Tests in ...

However, the evidence supporting some of the conclusions remains incomplete, and further mechanistic studies are needed to clarify how miR-283 affects normal aging and influences exercise adaptations.

This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...