There are also several other notable names who will be game-time decisions, such as Los Angeles Chargers quarterback Justin Herbert, New York Giants pass rusher Brian Burns and Cleveland Browns offensive tackle Jedrick Wills.

This year, the injury bug has bitten all 32 teams – and a lot more fantasy teams – a bit hard. Rams wideouts Cooper Kupp and Puka Nacua, along with 49ers weapons Christian McCaffrey and Deebo Samuel are some of the high-profile names that are going to miss Week 3 and beyond.

Herbert injured his right leg in the third quarter of Week 2’s 26-3 win against the Carolina Panthers trying to escape the pocket. He walked off the field but returned to the game. Chargers coach Jim Harbaugh said X-rays came back negative. He was a limited participant on Thursday.