Constructor HD was actually delayed multiple times, so System 3 presumably encountered some difficulties in development.

The acclaimed Nintendo 3DS JRPG Bravely Default is set to be a Nintendo Switch 2 launch game, with Bravely Default Flying Fairy HD Reamster.

Targeting revascularization via tryptophan-indole-NETs axis: the synergistic power of acupuncture and rt-PA thrombolysis in ischemic stroke ...