The enzyme dipeptidyl peptidase-4 (DPP-4 ... the strategy to inhibit the enzyme has been explored. Several DPP-4 inhibitors are in clinical development; these are orally active and increase ...

Alogliptin (NESINA), a dipeptidyl peptidase IV (DPP-4) inhibitor, was approved by the FDA on January 25, 2013 to improve blood sugar control in adults with type 2 diabetes. This drug had been ...

For patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with ...

For patients with nephrolithiasis, sodium-glucose cotransporter-2 (SGLT-2) inhibitor use is associated with a reducti ...

Egypt: A recent randomized controlled trial has demonstrated that sitagliptin, a DPP-4 inhibitor, significantly improves ...

Background: Antigen presentation to CD4+ T cells plays a critical role in heart failure (HF). Dipeptidyl peptidase 4 (DPP4) has been shown to promote the activation of T lymphocytes. This study aims ...

Introduction: Dipeptidyl amino-peptidase 3 (DPP3) is an aminopeptidase released into the bloodstream following cell death. Studies have demonstrated that in patients experiencing cardiogenic shock (CS ...

DPP Secretary General Kazuya Shimba said that Tamaki has his party’s full backing to stay on as leader after a report earlier Monday alleging marital infidelity. Shimba said the party will ...

In a stunning development, Democratic Party for the People (DPP) leader Yuichiro Tamaki admitted to an extramarital affair Monday morning after a tabloid magazine published photos of him and the ...

Liberal Democratic Party policy chief Itsunori Onodera, back right, and his Democratic Party of Japan counterpart Makoto Hamaguchi (back, L) attend a meeting in Tokyo on Nov. 8, 2024. (Kyodo ...

Was rumored for a 2025 release, but that has since been cast into doubt The iPhone SE 4 could be the biggest upgrade yet for Apple's mid-range SE line, with a new design and a wealth of new ...