An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

A key feature of cancer cells is their forced proliferation, which causes a hasty uncontrolled start of DNA replication. To date, however, little is known about the mechanisms that control the start ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

Abstract: Presents corrections to the paper, Corrections to “Label Free DNA Detection Techniques Using Dielectric Modulated FET: Inversion or Tunneling?”.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Corneal diseases can cause severe visual ...

A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication. Cell lines ...

In their new study, the researchers studied the DNA replication patterns in early embryos. "We discovered differences in the replication mechanisms of maternal and paternal DNA during the initial ...