Finally, chiral SFG is sensitive to macroscopic chirality but not local chiral centers and thus can detect not only canonical antiparallel double helix but also other DNA secondary structures, such as ...

Abstract: We introduce a three-dimensional (3-D) parametric active contour algorithm for the shape estimation of DNA molecules from stereo cryo-electron micrographs. We estimate the shape by matching ...

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Homologous recombination (HR) is one of the key DNA repair pathways in cells. It is essential for repairing double-stranded ... "We have obtained a cryo-electron microscopy structure that captures ...