Weather looks set to play a role in the Buffalo Bills' Week 13 matchup with the San Francisco 49ers.

And as the Bills prepare for a Sunday night game against the San Francisco 49ers, those temperatures are sure to be low and ...

The Factory House on Tecumseh Road East has scored big with the Detroit Lions as it prepares for its upcoming watch party.

The sounds of Christmas in downtown Lawrence aren’t always coming from a caroler or a brass horn. On one Saturday a year, it ...

Now that the holiday season is in full swing, several Bills players are taking the time to be active in the community. A ...

The region's largest business group is moving to 79 Perry St., a Pegula-owned building in the Cobblestone District, next door ...

Tight end Dalton Kincaid was held out with a knee injury Wednesday as the Bills returned to practice following their bye week. Right tackle Spencer Brown (ankle) and ...

The Buffalo Bills have +700 odds to win the Super Bowl, fourth-best in the NFL as of Nov. 25. The Bills knocked off the Kansas City Chiefs 30-21 in their most recent game. Josh Allen had 262 yards ...

Every week, Thad Brown answers your questions live from Orchard Park about the Bills and their next game. This week, Buffalo ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

From 5 a.m. to 10 a.m., traffic will be restricted on Delaware Avenue from Hertel Avenue to Comet Avenue. From 5 a.m. to noon ...

Black Friday has become something of an anachronism in the e-commerce era. The day after Thanksgiving marks the official ...