The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...

For the first time this NFL season, Buffalo has put up the bat signal for the Bills Mafia's assistance. Which of course means ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The snow may taper off by kickoff, but conditions ahead of the Bills game Sunday night could still make travel difficult.

ORCHARD PARK, N.Y. -- Get out your shovels, everyone. It's officially that time of year again in Western New York.

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the ...

Brock Purdy remained limited in a Thanksgiving Day practice, keeping his status in doubt for the 49ers’ game Sunday at ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

"Sunday Night Football" in Week 13 sees the San Francisco 49ers taking on the Buffalo Bills. Here's the latest on a snowy ...

Weather looks set to play a role in the Buffalo Bills' Week 13 matchup with the San Francisco 49ers.

Kansas City Chiefs quarterback Patrick Mahomes has been fined more than $14,000 for pantomiming what the NFL deemed a ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...