An engineered enzyme is at the center of a new method to visualize molecular details in human cells, and how these molecules ...

Our data suggest a mechanism by which mycobacterial ribosomes can discriminate mischarged tRNAs and that 16S rRNA differential methylation by ... could better discriminate against misacylated-tRNA.

Ribosomes are composed of a large subunit called the 50S and a small subunit called the 30S, each of which is made up of its own specific rRNA molecules ... all species. tRNA is the smallest ...

tRNA modifying enzymes, and rRNA molecules – many of which are redundant in terms of gene copy number or function. It has been hypothesized that the redundancy evolves under selection, driven by its ...

A comparative analysis of circular RNA reveals that the Rnl-knockout strain represses circularization of C/D box sRNAs without affecting the circularization of tRNA and rRNA processing intermediates.

Recent discoveries that abrupt amino acid starvation of Escherichia coli, accompanied by very high levels of ppGpp, occasion surprising instabilities of transfer RNA (tRNA), ribosomal RNA (rRNA), and ...

Nascent pre-rRNA molecules are immediately bound by proteins ... and base modifications as indicated below: The tRNA processing takes place in the nucleoplasm and are transmitted to the cytoplasm ...

Ribosomal RNA, or rRNA, is a part of the ribosome that plays a direct role in linking protein building blocks called amino acids. Humans have four kinds of rRNAs. Transfer RNA, or tRNA ...

The extinction of group I introns in Archaea would then be a consequence of recruitment of the tRNA splicing endonuclease. We deal here with comparative genome analysis, focusing specifically on the ...

This review focuses on normal hearing mechanisms, the basic mitochondrial genetics, and the most common mutations associated with hearing loss in mitochondrial rRNA and tRNA genes. We also briefly ...

Thus, during stage 3, the tRNA is sterically guided, paused, and stopped by 23S rRNA. Of the 68 nucleotides in the 23S rRNA that were observed to interact with the aminoacyl-tRNA during our ...