Urothelial bladder cancer constitutes one of the most common malignancies of the urinary tract, comprising 90-95% of urothelial carcinomas. Only 25% of patients present with muscle-invasive bladder ...

Testicular radiation exposure has been linked to diminished spermatogenesis, male infertility, and potentially testicular cancer. Despite this, the risk of testicular exposure from intraoperative ...

Neoadjuvant chemotherapy prior to radical cystectomy is a standard of care in patients with muscle-invasive bladder cancer. A retrospective multicenter study examined the contributions of preoperative ...

Two thirds of renal cell carcinoma (RCC) patients have localized disease at diagnosis. A significant proportion of these patients will relapse. There is a need for prognostic biomarkers to improve ...

We hypothesized that among non-organ-confined (NOC, T3-4 and/or N1-3) non-urothelial carcinoma of urinary bladder (non-UCUB) patients, bladder-sparing non-surgical management (NSM) provides ...

This study aimed to develop and evaluate a non-invasive XGBoost-based machine learning model using radiomic features extracted from pre-treatment CT images to differentiate grade 4 renal cell ...

Several studies have identified bacteria and other microbes in the bladder and lower urinary tract in the absence of infection. In women, the urinary microbiome has been associated with lower urinary ...

Penile cancer is a rare, aggressive malignancy, with incidence varying geographically. The primary risk factor is HPV infection. Squamous cell carcinoma represents the most common histological subtype ...

Metastatic clear-cell renal cell carcinoma (mccRCC) remains a major cause of morbidity and mortality among patients with kidney cancer. Over the past two decades, mccRCC treatment has significantly ...

Despite significant progress in the diagnosis and treatment of renal cell carcinoma (RCC), approximately 20% of patients present with metastatic disease, and up to 30% of patients with localized ...

Patients with pelvic lymph-node metastasis (PLNM) or extra-nodal extension (ENE) are classified as being in the pN3 stage according to the 8th edition of the AJCC/UICC TNM classification. While ...

The main rationale for confirmatory biopsies is to identify prostate cancer missed by initial sampling, typically in patients diagnosed with grade group (GG) 1 disease, to assess eligibility for ...