In past decades, numerous emerging infectious diseases have markedly affected global health and social-economic development. Consequently, the concept of “disease X” has been developed, and lists of ...
The recent article by Wang et al. represents a significant advancement in our understanding of the genetic and molecular underpinnings linking chronic obstructive pulmonary disease (COPD) and ...
A six-variable nomogram – comprising patient age, New York Heart Association (NYHA) class, serum sodium, platelet count, guideline-directed medical therapy intensity, and peri-procedural NOAF – ...
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by the Dabie bandavirus, commonly known as the SFTS virus (SFTSV). Since the initial discovery of SFTSV in ...
Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders. Blocking PDE4 activity ...
The datasets used in this study can be obtained from the publicly available FinnGen profiles, UK Biobank, eQTLGen, GEO database, and IEU open GWAS database. Zhu P, Ke ZR, Chen JX, Li SJ, Ma TL, Fan XL ...
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Many studies have reported that obesity causes heart failure (HF) pathogenesis. The elevated circulating levels of angiopoietin-like protein 2 (ANGPTL2) observed in patients with HF suggest potential ...
Background: With distal transradial access (dTRA), the postoperative compression time remains significantly longer than the recommended range via in practice. This study investigated whether ...
Our patient, an 84-year-old man with no significant risk factors and no history of smoking has been under medical care since 2012 for mild-to-moderate mitral regurgitation and mild tricuspid ...
Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational changes induced by protein mutations is the standard approach used ...
The threat of infectious diseases caused by pathogenic microorganisms to both human health and the economy is enormous. Coronavirus Disease 2019 (COVID-19) remains a global pandemic. In contrast to ...