Under this two-hit model, Brugge says, one normal copy of BRCA1 ought to be able to carry out DNA repair even when the other copy is inactivated by an inherited mutation. This means that a total loss ...

The heart tissue showed upregulation of molecular pathways that help recruit and retain immune cells involved in inflammation. Patients with active disease also had greater abundance of clusters of ...

HMS alumni Keith Dunleavy, founder and CEO of health care technology company Inovalon, and his wife, Katherine Dunleavy, a ...

Breast cancer rates rose by 1 percent per year from 2012-2021 for all U.S. women combined, with steeper increases for women under 50 and Asian American and Pacific Islander women, according to the ...

The results, published Nov. 7 in Current Biology, reveal that some of the stories told for decades about the individuals’ ...

Our educational programs advance Harvard Medical School's core mission to alleviate human suffering by nurturing a diverse group of leaders and future leaders in both clinical care and biomedical ...

Marcia Haigis, Ph.D., Professor of Cell Biology in the Blavatnik Institute at Harvard Medical School, served as the inaugural Director of Gender Equity for Faculty in Science at HMS. In her role, she ...

David Walt, the Hansjörg Wyss Professor of Bioinspired Engineering at HMS and professor of pathology at Brigham and Women’s Hospital, is operating at a microscopic level, observing cell abnormalities ...

Vivian Kobusingye Birchall, SM, is the host of ActonTV’s Health Care Blind Spots Series, where she interviews stakeholders, physicians, researchers, and industry policymakers on the status of cancer ...

CHASERR is unlike traditional genes, which are used as blueprints for making messenger RNA and proteins that perform various functions in cells. Instead, CHASERR codes for a long noncoding RNA, or ...