Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco 49ers (1-1) Sunday afternoon at SoFi Stadium. The list of issues thus far for the Rams is probably as long as their injury report.

The San Francisco 49ers (1-1) are 6.5-point favorites when they visit the Los Angeles Rams (0-2) in an NFC West matchup on Sunday, September 22, 2024 at SoFi Stadium.NFL odds courtesy of BetMGM

The reigning NFC champions faced a puzzling loss on Sunday. The San Francisco 49ers lost to the Minnesota Vikings 23-17 as star running back

San Francisco 49ers quarterback Brock Purdy is still making quite an impact in the state of Iowa despite being three years removed from his playing days for the Cyclones. Purdy and the Niners will play in one of three games that will air on Fox during the later slate of games at 1 p.

The 49ers QB became a better vocal leader this offseason. How will that help him overcome injuries to Deebo Samuel Sr. and Christian McCaffrey?

Mike Florio was the lowest on the Vikings following their Week 1 victory, but he jumped them 13 spots in his rankings to No. 11. He called them the "worst team in the division on paper," but they're all alone in first place.

Here's where the San Francisco 49ers and the rest of the NFL stand in the latest power rankings heading into Week 3.

Here are Newsweek Sports ' NFL power rankings ahead of Week 3. The Chargers are yet to play a good team, but they're taking advantage of playing bad ones. They've outscored the Raiders and Panthers by 35 points (48-13),