Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers ‘ season finale versus the ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, ...

Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.

The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?

There wasn’t much to play for when the San Francisco 49ers and Arizona Cardinals suited up Sunday at State Farm Stadium. The ...

San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury ...

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the ...

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL injury.

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...