These viruses have only the capsid surrounding their genetic material. A virus budding from a host cell membrane. This sequence of steps forms the virus’s envelope. A host is an organism that a ...

Aligos Therapeutics is a clinical-stage biotechnology company focused on improving patient outcomes through best-in-class ...

Local Rule-Based Theory of Virus Shell Assembly. Proceedings of the National Academy of Sciences of the United States of America, 1994. 91(16): p. 7732-7736. Elrad, O. M. and M.F. Hagan, Mechanisms of ...

Unlike traditional antiretrovirals that target enzymes such as reverse transcriptase or protease, LEN binds directly to the capsid protein, disrupting several critical steps in the virus’s life cycle.

Moreover, because at least 16 different hemagglutinin subtypes and nine different neuraminidase subtypes have been characterized, many different combinations of capsid ... of this virus's outbreak ...

AI-assisted adeno-associated virus (AAV) capsid engineering has transformative potential in terms of accelerating and optimizing the development of gene therapies. That’s the view of Fangzhi Tan ...

The Zika virus builds tiny tunnels, called tunneling nanotubes, to stealthily transport material needed to infect nearby ...

The firm said this view is based on encouraging efficacy to date, the use of a different adeno-associated virus capsid and transgene versus Elevidys, and a clean safety profile to date, with no ...

A combination of imaging techniques reveals how herpes simplex virus type 1 assembles within infected cells, highlighting the roles of essential viral proteins in viral assembly and exit.

The 3.0 Å resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the ...