palpable purpura or leg ulcers), or due to lymphocytic infiltrate (such as sicca symptoms, hypothyroidism, interstitial lung disease, splenomegaly, or lymphadenopathy). RA is a clinical diagnosis ...

More recently, rituximab, a B cell directed therapy, was reported to have efficacy for sicca symptoms or pulmonary, neurologic involvement. In this article, we demonstrate current diagnosis and ...