Objective The aetiology of primary biliary cirrhosis (PBC) is largely unknown. Previous studies have indicated that both environmental and genetic risk factors may be important. Design We undertook a ...

The FDA has accepted for review the NDA for linerixibat for the treatment of cholestatic pruritus in patients with primary biliary cholangitis.

Histopathological study of primary biliary cirrhosis and the effect of ursodeoxycholic acid treatment on histology progression. Hepatology 29 , 1007–1012 (1999). Article CAS Google Scholar ...

A drug might look promising in one clinical trial and fail in another. That was the case for aducanamab (Aduhelm) , the Alzheimer’s drug that was approved by the FDA in 2021 despite the concerns ...

Infectious disease clinicians raised alarm that proposed cuts to Medicaid could affect ID-related services, not only among patients using the program but also patients with private health insurance.

Need to Know He spotted weight-loss drugs and AI before they became hot. Here’s this investor’s next big idea. Citrini Research’s James van Geelen sees future robots cleaning your house ...

Shares of BioNTech SE were soaring in early Monday trading, after Bristol Myers Squibb Co. made an $11.1 billion splash in the rapidly growing new cancer-drug game.

Objective This randomised trial aimed to address whether endoscopic variceal ligation (EVL) or propranolol (PPL) is more effective at preventing initial oesophageal variceal bleeding (EVB) in patients ...

Pruritus can occur at any stage of PBC disease or biochemical control, and is experienced in varying degrees of severity by up to 90% of people living with PBC. 1 The first line treatment for PBC ...

Otsuka Pharmaceutical has shared more detailed data behind its kidney disease drug’s phase 3 win, showing the monoclonal antibody halved patients’ urine protein-to-creatinine ratio (UPCR ...

7) Salvarsan -- The Cure for Lust. Chances are, Salvarsan didn't make your list of most important drugs. But historians Swann and Greenberg say it belongs in the club.

Border officials seized 50,000 kilos of Chinese precursor chemicals intended for Mexican cartels, part of China's broader strategy to undermine U.S. security.