The best Mini-ITX board of all is the Asus ROG Strix X870-I Gaming WiFi.An AMD AM5-compatible motherboard that will pair nicely with one of the best CPUs for gaming.On Intel's side of the aisle ...

The Mini-ITX size makes them useful as home theater PCs, portable workstations, and even media servers, proving that a board doesn't have to be big to be impactful. There are some trade-offs, though.

Mini-ITX cases are limited on space, compared to regular M-ATX or full-size ATX cases. ... Most modern mini-ITX motherboards have at least two M.2 slots, so make sure you utilize them.