People with unresponsive chronic migraine and obesity experienced substantial relief after they started taking a GLP-1 drug, researchers in Italy have found.

For adults with obesity and migraine, liraglutide reduces migraine burden, with reductions in mean monthly headache days.

Liraglutide, like LirAzo, is a synthetic analog of the natural incretin GLP-1, and both drugs recognize and bind to the GLP-1 receptor on the surface of pancreatic beta-cells.

Liraglutide is sold as the weight-loss drug Saxenda and as the diabetes medication Victoza, ... possibly combined with an ability to bind to the GLP-1 receptor more strongly than older drugs. ...

GLP-1 agonists bind to GLP-1 receptors in the body, ... Another study on the effectiveness of liraglutide found that 62% of participants lost at least 5% of their body weight after six months, ...

The class of drugs liraglutide and semaglutide belong to are known as GLP-1 mimetics, meaning they mimic the natural hormone GLP-1. This hormone is released from your small intestines in response ...

Although semaglutide, liraglutide, and tirzepatide all work by blocking GLP-1 to curb hunger signals, tirzepatide may be the ...

GLP-1 Agonist Peptides against Type 2 Diabetes Are Promising Targets for Patients with Poor Hb1Ac Control Type 2 diabetes is a major risk factor for cardiovascular disease related morbidity and ...

Liraglutide is an analog with 97% homology to human glucagon-like peptide (GLP-1) and acts as a GLP-1 receptor agonist. Several large, randomized, multicenter phase 3 trials evaluated the efficacy ...