For new GRAS substances, notification to the FDA is voluntary. 2,3 Manufacturers may opt to submit a premarket GRAS notification to the FDA with evidence showing that the substance is generally ...

Most state animal food programs in the U.S. recognize GRAS substances that have been formally filed and reviewed by the FDA's Center for Veterinary Medicine, but some states do not accept or ...

The FDA’s GRAS rule lets companies decide if food additives are safe—without agency oversight. RFK Jr. now aims to close this loophole, requiring companies to notify the FDA of new ingredients ...

GRAS or "generally recognized as safe" was created in 1958 under the Food Additives Amendment to the Federal Food, Drug, and Cosmetic Act. GRAS was applied to safe, commonly used ingredients in food.

Kennedy’s order to close the GRAS loophole comes before the FDA has a commissioner in place. President Donald Trump nominated Johns Hopkins Hospital surgeon Marty Makary for the position, but ...

It’s time to revamp the FDA’s “generally recognized as safe,” or GRAS, program that allows companies to add untested ingredients to food, the Health and Human Services secretary says. That ...

Nine of 29 FDA staffers charged with reviewing the safety of food additives were dismissed over the weekend, said Jim Jones, who was head of the agency’s food division until he resigned this week.

The FDA established a list of GRAS substances and added new items if they passed a safety review. Individuals from outside the agency also could ask to have a particular substance studied for ...

With GRAS approval, the FDA has confirmed that Oobli's protein-based sweetener monellin, a novel sweet protein, is safe to be used as a sweetener in food and beverages.