Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran ...

In a manuscript published today in the American Journal of Psychiatry titled "Long-Read Genome Sequencing in Clinical ...

City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting transcription-replication conflicts to combat treatment resistance.

These are areas with an accelerated rate of mutations often associated ... restructuring of large portions of the chromosomes. Segmental duplications are enriched in the short arms of certain ...

Researchers at City of Hope have identified a new molecular target for treating pancreatic cancer, reports a Gastroenterology ...

Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S.

A new study focused on transcription-replication conflicts, which occur when mechanisms responsible for gene expression and genome duplication collide.

The locus-specific mutation frequencies for copy number ... homologous events leading to copy number variation. Deletions and duplications of chromosomal segments (copy number variants, CNVs ...