These project from the arcuate nucleus to other key hypothalamic nuclei, such as the paraventricular, dorsomedial, ventromedial and lateral hypothalamic nuclei. There are also projections to and ...
However, the cellular mechanisms by which MC4R regulates reproduction are unknown. Kiss1 neurons directly stimulate gonadotropin-releasing hormone (GnRH) release through two distinct populations; the ...
Type 1 – inhibited by serotonin. Type 2 – excited by serotonin and adenosine. As adenosine accumulates during wakefulness [12] [17] it is likely that type 2 cells play a role in sleep induction. The ...
1 Circadian Rhythms Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany 2 Genes & Behavior Department, Max Planck Institute for Biophysical Chemistry ...
Despite the increasing number of anti-hypertensive drugs have been developed and used in the clinical setting, persistent deficiencies persist, including issues such as lifelong dosage, combination ...
1 First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China 2 Inflammatory Bowel Disease Center/Department of Colorectal Surgery, Jiangsu Province Hospital of Chinese ...
Anxiety is an adaptive response that promotes harm avoidance, but at the same time excessive anxiety constitutes the most common psychiatric complaint. Moreover, current treatments for anxiety—both ...