John and Jim Harbaugh have met as head coaches on the biggest stage in football, colliding back in Super Bowl 47.

The San Francisco 49ers haven't been an underdog for a game since 2022, but that incredible run appears to be coming to an ...

How have Super Bowl odds changed over the last week? Let's take a look at the most recent sports betting odds for Super Bowl ...

The New England Patriots achieved the longest NFL postseason streak from 2009-2019. Which other teams make the list? Check ...

Week 12 of the 2024 NFL season features some wild upsets, including the Cleveland Browns taking down the Pittsburgh Steelers ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

After the San Francisco 49ers' crushing 38-10 defeat to the Green Bay Packers on Sunday, Eric Branch of the San Francisco ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

Following their loss in Week 12 to the Packers, Colin Cowherd stirred the pot, giving his honest take on an 'old, aging' ...

The Bills and 49ers meet on Sunday Night Football in a game with playoff implications for both teams. Here are three ...

The 49ers have always been "better together." Take one key player away, they look weaker. Take two players away, they look ...

The San Francisco 49ers are 5-6 after a brutal loss to the Green Bay Packers in Week 12. With the playoffs slipping away, ...