Huntington, surprising mechanism
Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder
Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding of the fatal neurodegenerative disorder and suggest potential ways to delay or even prevent it.
New findings shed light on cause of Huntington's disease progression
A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time, but doesn't start causing harm until it hits a toxic threshold that rapidly leads to the nerve cell’s death.
New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's ...
Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though ...
About 2,000 people in Australia are affected by Huntington's disease, a fatal and incurable condition that affects the ...
But Huntington’s second, self-preserving, oddity is that unlike most genetic disorders it rarely manifests until well into ...
Having 35 copies of the CAG triplet in the gene that causes Huntington’s disease is not a problem. Inheriting 40 could be a ...
A new study highlights the potential of a therapeutic strategy focused on stopping or slowing Huntington's disease.
Why do people who inherit the brain disease Huntington’s often only show symptoms well into adulthood, between 30 and 50 ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback