The Hoosiers jumped out to an early lead when quarterback Kurtis Rouke handed the ball off to Ty Son Lawton, who scored the game's first touchdown. However, this lead was short-lived, as the Buckeyes' defense quickly took control.

The Buckeyes thoroughly outclassed previously unbeaten Indiana, 38-15, to earn a victory that moves them within striking distance of reaching the Big Ten Championship game for the first time since 2020.