An arctic blast will send temperatures across the United States plummeting as bitterly cold air that originated in Siberia will arrive from Canada by week’s end, bringing with it dangerously cold wind chills for millions of Americans.

Snow and winds are likely to trigger flight cancellations and cause headaches for people traveling to DC for Inauguration Day.

A blast of Arctic air is set to cover much of the United States with temperatures below freezing starting on Friday and into next week, impacting millions of Americans in nearly all of the contiguous states.