Astellas Pharma (ALPMY) and Sangamo (SGMO) announced they have entered into a license agreement allowing Astellas to leverage Sangamo’s neurotropic adeno-associated virus capsid, STAC-BBB ...

For many years, scientists have explored the structural changes of the virus capsid which encases the genome. In contrast, much less is known about the virus matrix—the outer protein shell ...

The basic components of a virus are genetic material and a protein shell, called a capsid, that surrounds and protects the fragile nucleic acids. During the life cycle of a virus, the genetic material ...

Local Rule-Based Theory of Virus Shell Assembly. Proceedings of the National Academy of Sciences of the United States of America, 1994. 91(16): p. 7732-7736. Elrad, O. M. and M.F. Hagan, Mechanisms of ...

Moreover, because at least 16 different hemagglutinin subtypes and nine different neuraminidase subtypes have been characterized, many different combinations of capsid ... of this virus's outbreak ...

Bay Area drug giant Gilead is plotting the trial of a groundbreaking, once-a-year HIV prevention drug lenacapavir.

Unlike traditional antiretrovirals that target enzymes such as reverse transcriptase or protease, LEN binds directly to the ...

The virus is composed of three layers—a capsid that contains the viral DNA, a protein layer called the tegument and an outer envelope that is studded with viral glycoproteins (proteins with a ...

Leerink reiterated an Outperform rating and $24 price target on Regenxbio (RGNX) after Sarepta (SRPT) announced a Duchenne muscular dystrophy ...

The Zika virus builds tiny tunnels, called tunneling nanotubes, to stealthily transport material needed to infect nearby ...

The 3.0 Å resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the ...

Unlike traditional antiretrovirals that target enzymes such as reverse transcriptase or protease, LEN binds directly to the capsid protein, disrupting several critical steps in the virus’s life ...