Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA ...

Greenland sharks are large, mysterious creatures that roam the chilly waters of the north Atlantic and Arctic oceans. These elusive animals are considered the longest-living vertebrates on the planet, ...

To date, no study of a sufficient size has reported a significant association between SNPs at the TP53 locus and altered ... The biological effects of p53 pathway variants at the molecular level ...

For example, MDM2 binds to TP53 mRNA, controlling the rate of translation ... The biological effects of p53 pathway variants at the molecular level in primary cells or in vivo still need to ...

When the pathway is disrupted ... In particular, they found that the sharks carried an altered version of the TP53 gene, which helps suppress tumors and repair DNA. Those findings, published ...