New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...
Munoz, and Fred Bunz from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine studied the tumor-suppressing protein p53, which plays a key role in ...
One such mechanism involves a protein called p53. Often dubbed the "guardian of the genome," this protein plays a pivotal ...
Munoz, and Fred Bunz from the Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine studied the tumor-suppressing protein p53, which plays a key role in ...
In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and ...
p53 controlla queste delicate operazioni, in concerto e in associazione con altre proteine fondamentali. Nei tumori, p53 viene persa o più di frequente si ritrova in forma mutata. Da guardiano ...
New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...
Navtemadlin is an MDM2 inhibitor that can help to kill cancer cells by boosting the activity of p53, a protein that controls cell growth and induces cell death in response to DNA damage.
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