Platelets are an important part of the atherothrombotic process. They are involved in the pathways leading to atherosclerosis formation and progression and are central to the development of thrombus ...

Inherited platelet disorders represent a heterogeneous group of genetic conditions that affect the number, size, or function of platelets, with clinical manifestations ranging from mild mucocutaneous ...

Thrombocytopenic disorders include numerous causes of decreased platelet production or increased platelet destruction. Having too few platelets can lead to internal or serious bleeding after surgery ...

Over two dozen cases of the rare blood disorder thrombocytopenia have been reported in people who have received COVID vaccines in the U.S. However, a link between COVID vaccines and the disease that ...

Noncancerous blood disorders are conditions that affect blood cells, such as red blood cells, white blood cells, and platelets. Blood disorders may cause symptoms and complications, but most are ...

A new miniature 3D model of human bone marrow has just been described. The model may help clinicians predict which patients will benefit from a new therapy for blood platelet disorders, such as ...

Neonatal alloimmune thrombocytopenia (NAIT) is a disorder that affects pregnant people and their fetuses. It occurs when the birthing parent’s immune system produces antibodies that attack and destroy ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an autoimmune ...

Up to 1,000 additional blood platelet donors are needed in the coming year to meet demand, as "there is no substitute for platelets".

Abstract and Introduction Review of Normal Platelet Physiology and Megakaryocytopoisis Qualitative Platelet Abnormalities Conclusion References Nitric oxide (NO) is another drug used in the neonatal ...