RPE cells displaying cobblestone morphology. Cells were immunolabeled with tight-junction ZO-1 marker (shown in green) and co-stained with nuclei marker, Hoechst (shown in blue). Image Credit: ...

Researchers identify five distinct cell subpopulations in the retinal pigment epithelium using artificial intelligence (AI), which could explain different severities of retinal degenerative diseases.

Age-related macular degeneration (AMD) represents a leading cause of vision loss in the elderly, primarily due to the degeneration of the retinal pigment epithelium (RPE), a specialised cell layer ...

Scientists at the National Eye Institute (NEI), part of the NIH, say they have determined how peptides can protect neuronal cells found in the light-sensing retina layer at the back of the eye. The ...

In a recent study published in the International Journal of Molecular Sciences, researchers identified that loss of pigment epithelium-derived factor (PEDF) might cause aging in the eye. The retina is ...

FORT LEE, N.J.--(BUSINESS WIRE)--Luxa Biotechnology LLC (Luxa), a clinical-stage biotechnology company developing a novel adult retinal pigment epithelial stem cell (RPESC) therapy for dry age-related ...

Japan’s Pharmaceutical and Medical Devices Agency has cleared Healios K.K. and Sumitomo Pharma Co. Ltd. to begin a phase I/II study of HLCR-011, which is composed of retinal pigment epithelial (RPE) ...

Retinal degeneration leads to irreversible vision loss, significantly impacting quality of life. Approximately 19.83 million Americans over 40 have age-related macular degeneration (AMD), a leading ...

CARLSBAD, Calif.--(BUSINESS WIRE)--Lineage Cell Therapeutics, Inc. (NYSE American and TASE: LCTX), a clinical-stage biotechnology company developing allogeneic cell therapies for unmet medical needs, ...