The cytoskeleton of eukaryotic cells is made ... out from the centrosome to provide the basic organization of the cytoplasm, including the positioning of organelles. The protein actin is abundant ...

which leads to the exciting hypothesis of the chaperone–cytoskeleton complex as the guardian of the cytoplasm in stressed cells. Finally, a physiological role for small HSPs has been identified ...

In the cytoplasm, actin has a well-established role as a component of the cytoskeleton, and plays important roles for example in cell motility and morphology. In the nucleus, actin has been linked to ...