Matrix 2 (M2) is a helical proton channel that regulates influenza’s internal pH as it passes through different host membranes. The Orthomyxoviridae family classifies four major types of influenza ...

Two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA), and the M2 ion-channel protein are embedded in the viral envelope, which is derived from the host's plasma membrane.

The influenza M2 viroporin is already a clinically approved antiviral drug target. In other coronaviruses, the E protein viroporin which is involved in growth, could be a potential target for COVID-19 ...

Feb. 15 (UPI) --All age groups in the United States are experiencing a "high severity" of influenza cases among all age groups for the first time since the 2017-18 flu season, the Centers for ...

Computer generated 3D model, showing a cross-section of the green RNP spirals, blue hemagglutinin, red neuraminidase, and purple m2 ion channels that constitute the structure of the Influenza A ...

Influenza A virus particles strategically adapt their shape -- to become either spheres or larger filaments -- to favor their ability to infect cells depending on environmental conditions ...

Influenza has historically been an uncommon illness in the newborn period, although epidemic outbreaks in neonatal intensive care units have been described. There is currently significant concern ...