Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

and the opportunities currently under development to achieve the goal of HBV cure (bottom). cccDNA, covalently closed circular DNA; 3D, three-dimensional; DCs, dendritic cells; FNAs, fine-needle ...

It is notable that even in HBV patients who have achieved a functional cure, chronic HBV can be reactivated by suppressing the immune system 4. We hypothesize that reducing antigen levels to ...