This forms two replication forks that move along the ... Also, whereas bacterial chromosomes are circular, eukaryotic chromosomes are linear. During circular DNA replication, the excised primer ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

Arrested replication forks are prone to collapse, posing serious threats to genomic integrity, suggesting that DNA replication problems are critical ... that are highly conserved amongst most ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery ... the normal progression of ...

Chen “P53 Inhibits Strand Exchange and Replication Fork Regression Promoted by Human Rad51,” J. Mol. Biol., (2004) 336, 639 – 654. R. Deaton, J-W Kim and J. Chen “Design and Test of ...