A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

Rosalind Franklin was a brilliant physical chemist whose X-ray diffraction work revealed the structure of DNA with ...

Researchers discovered that stiff DNA segments inside nucleosomes physically block chromatin remodeling. The remodeling machinery normally shifts DNA by creating 20–30 base-pair loops, but these ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

James Watson, the scientist who co-discovered the structure of DNA, died on Nov. 6, 2025, at the age of 97 On a foggy Saturday morning in 1953, a tall, skinny 24-year-old man fiddled with shapes he ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...