Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have ...

PAG was shown to interact with beta-2 adrenergic receptors to influence how forcefully the heart muscle cells contract – a process that investigators believe contributes to heart failure.

The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...

Previous studies have identified the adrenergic receptor (AR)-binding potential of PAGln, which suggests its potential role in allosteric modulation. ARs are host receptors involved in a wide ...

The binding of adrenaline to an adrenergic receptor initiates a cascade of reactions inside the cell. The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme ...

PAG was shown to interact with beta-2 adrenergic receptors to influence how forcefully the heart muscle cells contract – a process that investigators believe contributes to heart failure.

Ephedrine sulfate is a sympathomimetic amine that directly acts as an agonist at α-and ß-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons.

The beta-adrenergic blockade did not alter these ... other sympathomimetic drugs could be accounted for if two sets of receptors, alpha and beta, were present in or near muscles and glands ...

USF faculty continually demonstrate their skills in conducting high-impact research and innovation to advance frontiers of ...

Top-line data from VEGA-3 Phase 3 trial expected in first half of 2025Top-line data from LYNX-2 Phase 3 trial in patients with decreased visual ...