The UN human rights chief said Israel's "means and methods of warfare" were inflicting "horrifying, unconscionable suffering".

Israeli fire killed at least 40 people, half of them near an aid distribution site operated by the U.S.-backed Gaza Humanitarian Foundation on Monday, the territory's health ministry said, as U.N. officials denounced Israeli-backed aid delivery methods.

Palestinians say Israeli forces opened fire on people trying to access a U.S.-backed group's aid distribution hub in Gaza, in the deadliest of such incidents reported to date.

Israel's blistering attack with warplanes and drones against Iran’s nuclear and military structure has sparking an open conflict between the two long-time foes that threatens to escalate.

Stock markets across the Gulf fell on Sunday morning after Israel and Iran launched fresh attacks on each other overnight, sparking fears of a widening conflict in the Middle East.

Iran has asked Qatar, Saudi Arabia, and Oman to urge U.S. President Donald Trump to influence Israel to agree to an immediate ceasefire, according to Reuters reports on Monday. In exchange, Tehran is offering flexibility in nuclear negotiations.