Huntington, surprising mechanism

Surprise finding sheds light on what causes Huntington's disease, a devastating fatal brain disorder
Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the brain to break down and die.
New findings shed light on cause of Huntington's disease progression
A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time, but doesn't start causing harm until it hits a toxic threshold that rapidly leads to the nerve cell’s death.
Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder
Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding of the fatal neurodegenerative disorder and suggest potential ways to delay or even prevent it.
Early brain changes in Huntington’s disease detected two decades before symptoms
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease,
'Unprecedented' brain study brings cure for Huntington's disease a step closer
A cure for Huntington’s disease may be a step closer after a study found brain changes linked to the condition could be detected 23 years before a diagnosis. Symptoms of the inherited disease typically emerge in midlife between the ages of 30 and 50.
Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease
Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.
New Research Sheds Light on the Causes of Huntington’s Disease
If you’ve ever heard of Huntington’s disease, you know how devastating it can be. This hereditary brain disorder slowly robs people of their ability to think, move, and even communicate. The disease’s progression is relentless,
Medical mystery solved: Why do some people develop Huntington's earlier than others?
New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...
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Unveiling Image of Never-Before-Seen Features of a Neuronal Disease
Researchers have mapped the unique structure of protein clusters in Huntington's disease, paving the way for improved ...
Experts hail 'milestone' in study of the deadly Huntington's disease
About 2,000 people in Australia are affected by Huntington's disease, a fatal and incurable condition that affects the ...
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New Understanding of How Genetic Mutation Causes Huntington’s Disease
Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though ...
Brain changes in Huntington’s disease decades before diagnosis will guide future prevention trials
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington’s ...
Scientists Unveil First Detailed Image of Huntington’s Disease Fibrils
Researchers mapped the unique structure of protein clumps in Huntington's disease, opening doors to better diagnostics and ...
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New Research Uncovers Delayed Effects of Genetic Mutation in Huntington's Disease Development
Recent findings uncover how Huntington's disease develops over time, revealing the mutation's delayed effects on brain cells.
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Studies reveal a new biology of Huntington’s, renewing drugmaker interest in therapies
A new study highlights the potential of a therapeutic strategy focused on stopping or slowing Huntington's disease.