Muscatine is a city in and the county seat of Muscatine County, Iowa, United States. The population was 23,797 at the time of the 2020 cen…Muscatine is a city in and the county seat of Muscatine County, Iowa, United States. The population was 23,797 at the time of the 2020 census, an increase from 22,697 in 2000. It is located along the Mississippi River. The local business association states that the name Muscatine is not used by any other community.
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